Biostatistics4

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Answere in Step by Step form!!!!

 

 

For problem below, state the null and the alternative hypothesis, determine a critical value, present a test statistic, and provide a p-value and your decision. Use (Type 1 error rate of  =.05)

 

 

  1. Question: Using the data below:
    1. Perform an appropriate test to determine if the variances for post-exposure FEV1 are different between hyperreactive and normal subjects.
    2. Using your result in part a, perform an appropriate test to determine if the means for post-exposure FEV1 are different between hyperreactive and normal subjects.
    3. Provide an interpretation of the test results in part b.
    4. Perform an appropriate test to determine if there is a significant average 00change in FEv1 from pre exposure to post exposure for normal subjects.

 

 

 

 

 

Data: D’alessandro et al. (A-47) wished to know if preexisting airway hyperresponsiveness (HR) predisposes subjects to a more severe outcome following exposure to chlorine. Subjects were healthy volunteers between the ages of 18 and 50 years who were classified as with and without HR. The following are the FEV(1) and specific airway resistance (Sraw) measurements taken on the subjects before and after exposure to appropriately diluted chlorine gas:

 

 

 

                             Hyperreactive Subjects

 

                 Pre-Exposure                      Post-Exposure      

 

Subject

FEV1

Sraw

 

FEV1

Sraw

1

3

5.8

 

1.8

21.4

2

4.1

9.56

 

3.7

12.5

3

3.4

7.84

 

3

14.3

4

3.3

6.41

 

3

10.9

5

3.3

9.12

 

3

17.1

 

 

 

 

 

                                     Normal Subjects

 

                Pre-Exposure                        Post-Exposure

 

Subject

FEV1

Sraw

 

FEV1

Sraw

1

4.3

5.52

 

4.2

8.7

2

3.9

6.43

 

3.7

6.94

3

3.6

5.67

 

3.3

10

4

3.6

3.77

 

3.5

4.54

5

5.1

5.53

 

4.9

7.37

 

 

 

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